镰刀型红血球疾病与脐带血
镰刀型红血球疾病与脐带血
镰状细胞疾病(镰状细胞性贫血)是一种基因异变引致的遗传病,患者的红血球变成不正常的镰刀形,并阻塞血液流动,相当具危险性。镰状细胞疾病估计影响全球超过200万人,现时造血干细胞移植是唯一能治癒此病的方法,脐血是其中一个干细胞来源。
由于镰状细胞疾病是隐性遗传的,即已有一个患镰状细胞疾病的孩子的母亲,下一个孩子有25%机会同样患上此病,亦有25%机会与患病孩子组织类型吻合而有机会可进行脐血移植,所以在下一个孩子出生时储存脐带血相当重要。
镰状细胞疾病(镰状细胞性贫血)是一种基因异变引致的遗传病,患者的红血球变成不正常的镰刀形,并阻塞血液流动,相当具危险性。镰状细胞疾病估计影响全球超过200万人,现时造血干细胞移植是唯一能治癒此病的方法,脐血是其中一个干细胞来源。
由于镰状细胞疾病是隐性遗传的,即已有一个患镰状细胞疾病的孩子的母亲,下一个孩子有25%机会同样患上此病,亦有25%机会与患病孩子组织类型吻合而有机会可进行脐血移植,所以在下一个孩子出生时储存脐带血相当重要。
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