Why the needs to store
umbilical cord and cord blood?

Immense potential for future
regenerative medicine opportunities

Medical Waste Vs “Precious Health Resources” ?

Since the first successful case of umbilical cord blood transplant 30 years ago in Paris for a boy with Fanconi anemia, a genetic and potentially life-threatening type of anemia, the medical community has continuously been studying, researching and conducting clinical trials on the umbilical cord blood application to save countless patients at crucial time. With the advancement of Bioscience, there is enormous potential for Regenerative Medicine using stem cells from umbilical cord blood.

Big decisions on banking for future hope of health, or abandoning the precious health resources?
Store NOW for your family’s future health assurance!

Read More

Understanding umbilical cord and cord blood

The umbilical cord connects a baby in the womb to its mother. It runs from an opening in the baby’s stomach to the placenta in the womb. The average cord is about 50 to 60 cm (20 inches) long and about 1 cm thick.
The umbilical cord carries oxygen and nutrients from the placenta into the baby’s bloodstream.
The umbilical cord is made up of:

  • one vein that carries blood rich in oxygen and nutrients from the mother to the baby
  • two arteries that return deoxygenated blood and waste products, such as carbon dioxide, from the baby back to the placenta

Towards the final stages of pregnancy, the placenta passes antibodies through the umbilical cord from the mother to the baby. These give the baby immunity from infections for about three months after birth. However, it can only pass on antibodies which the mother already has.

Cord blood is rich in hematopoietic stem cells, which assist the fetus’s growth through the manufacturing of blood (red blood cells, platelets and etc.) and enhance the immune system (lymphocytes, immune cells, etc.). In fact, the real therapeutic effect is not cord blood itself but cord blood stem cells.

Your baby’s cord blood stem cells are a perfect genetic match for your newborn, and they have a high probability of being a suitable match for siblings and parents. This eliminates the risk of transplant rejection (GVHD) for your newborn, and significantly reduces the risk of GVHD for immediate family members. SAVING your baby’s cord blood provides your family with the best chance of survival, recovery, and a renewed quality of life when facing a life-threatening disease or condition.

Umbilical cord and cord blood

Has been in use for more than 30 years worldwide

More than 40,000 transplant cases9

The world’s first case of cord blood transplant was done in 1988. Matthew Farrow, suffered from aplastic anemia (also known as Fanconi Anemia) when he was only 5 years old. He received cord blood transplants at Hôpital Saint-Louis, Paris, France. The cord blood came from his newly borne younger sister and the transplantation was very successful. Matthew is now healthy grown up, not only married and become a father to a child, he also works in a cord blood bank to share his story of cord blood saving and giving him a second change in life.

Read More

Stem cells are called “universal cells” in the medical community. In the past 20 years, the scientists and medical teams have been conducting researches and the application of stem cells in medical treatment and regenerative medicine. It has been proven that stem cells can treat as many as 113 diseases and regenerative treatments, including malignancies (cancers), blood, innate immune system disorders and metabolic disorders. In the lung disease, nervous system diseases, skin diseases and other medical research has made great breakthroughs and progress.

Read More

Stem cell has ultimate potential in health treatment

Treat more than 113 diseases and regenerative treatments2 ,3

The main difference between storing umbilical cord blood and umbilical cord

Items Umbilical Cord Blood Umbilical Cord
Source Umbilical cord blood is the excess blood from the cord and/or the placenta after baby is born The cord tissue from umbilical cord of your newborn baby also has an exceptional source of valuable stem cells which is vastly different from cord blood stem cells.
Stem cell types Stem cells derived from cord blood are called hematopoietic stem cells (HSCs). They are the building blocks of the body’s blood and immune systems. Stem cells from cord tissues are known as mesenchymal stem cells (MSCs). They have shown great potential in the fields of regenerative medicine, tissue engineering and gene therapy.
Clinical trial application and indications Cord blood’s Hematopoietic Stem Cells (HSCs) have the ability to repair and replace blood cells that has been damaged by diseases, chemotherapy or other medical conditions to treat blood, immune, metabolic diseases Mesenchymal stem cells (MSCs) from the cord tissues can differentiate into a variety of cell types, including bone, cartilage, muscle, nerve and others to treat tissues or organs degenerated by diseases. The use of cord tissue stem cells has the enormous potential to make regenerative medicine a life-saving reality.
Read More

Process: Painless, safe and reliable

Collection Procedure

1. Collection : Specialized and dedicated specimen courier team

Within 12 hours after notification from the expectant parents, our dedicated courier team will retrieve the umbilical specimens from the hospital of birth with a temperature control incubator and send it to our laboratory for processing and storage.

2. Identity Verification

Umbilical specimen collected shall be verified again upon reaching Cryolife’s laboratory to ensure accurate identify of the specimen against its rightful owner. A unique ID code shall be assigned to the sample as part of privacy protection.

3. Sample Retrieved

Before processing, a small portion of cord blood sample together with the maternal blood will be retrieved for stipulated tests covering infectious diseases and blood grouping.

4. Automated Processing

The red blood cells and plasma from the cord blood sample shall be removed to harvest the cord blood stem cells. This process is performed by AXP (AutoXpressTM Platform), an advance automated cell recovery system which is functionally closed and sterile, ensuring quality contamination control and efficient recovery of the mononuclear cells (MNCs) from the cord blood. After this process, a small concentrated cord blood aliquot is prepared for stipulated tests.

5. Controlled-Rate Freezing and Storage

After processing, cryoprotectant will be added to the processed cord blood unit and it will then be ready for long term cryostorage. The unit will undergo a slow freezing process at a controlled rate until it reaches -90'C before it is transferred to a vapour phase liquid nitrogen tank for long-term storage at -185C or lower. Guideline from AABB is to store at -150C or lower.

6. On-going Quality Assurance

CRYOLIFE conducts biannual (2 times per year) quality assurance program to ensure the quality of cryopreserved cord blood units in each storage tank. Terminated or dummy cryopreserved units will be retrieved and thawed for quality tests including cell viability and cord blood stem cell count. Cord blood stem cell activities are also analyzed by performing colony formation unit (CFU) assay.