Leukemia is a cancer of the blood immune system, where the cells are called leukocytes or white cells

Diagnosis	Allogeneic (Donor Cells)	Autologous (Own Cells)
Acute Lymphoblastic Leukemia (ALL)	✔
Acute Myelogenous Leukemia (AML)	✔
Acute Biphenotypic Leukemia	✔
Acute Undifferentiated Leukemia	✔
Chronic Lymphocytic Leukemia (CLL)	✔
Chronic Myelogenous Leukemia (CML)	✔
Juvenile Chronic Myelogenous Leukemia (JCML)	✔
Juvenile Myelomonocytic Leukemia (JMML)	✔

Myelodysplastic Syndromes are also called pre-leukemia

Diagnosis	Allogeneic (Donor Cells)	Autologous (Own Cells)
Refractory Anemia	✔
Refractory Anemia with Ringed Sideroblasts (Sideroblastic anemia)	✔
Refractory Anemia with Excess Blasts	✔
Refractory Anemia with Excess Blasts in Transformation	✔
Chronic Myelomonocytic Leukemia (CMML)	✔

Lymphoma is a cancer of the leukocytes that circulate in the blood and lymph vessels

Diagnosis	Allogeneic (Donor Cells)	Autologous (Own Cells)
Hodgkin’s Lymphoma	✔	✔
Non-Hodgkin’s Lymphoma (Burkitt’s Lymphoma)	✔

Other Disorders of Blood Cell Proliferation

Diagnosis	Allogeneic (Donor Cells)	Autologous (Own Cells)
Anemias are deficiencies or malformations of red cells:	…	…
Aplastic Anemia	✔
Fanconi Anemia (The first cord blood transplant in 1988 was for FA, an inherited disorder)	✔
Congenital Dyserythropoietic Anemia	✔
Paroxysmal Nocturnal Hemoglobinuria (PNH)	✔
Inherited Red Cell Abnormalities Red cells contain hemoglobin and carry oxygen to the body:	…	…
Sickle Cell Disease	✔
Beta Thalassemia Major (aka Cooley’s Anemia)	✔
Diamond-Blackfan Anemia	✔
Pure Red Cell Aplasia	✔
Inherited Platelet Abnormalities Platelets are blood cells needed for clotting:	…	…
Amegakaryocytosis / Congenital Thrombocytopenia	✔
Glanzmann Thrombasthenia	✔
Inherited Immune System Disorders: Severe Combined Immunodeficiency:	…	…
SCID with Adenosine Deaminase Deficiency (ADA-SCID)	✔
SCID which is X-linked	✔
SCID with absence of T & B Cells	✔
SCID with absence of T Cells, Normal B Cells	✔
Omenn Syndrome	✔
Inherited Immune System Disorders: Neutropenias	…	…
Infantile Genetic Agranulocytosis (Kostmann Syndrome)	✔
Myelokathexis	✔
Inherited Immune System Disorders: Other	…	…
Ataxia-Telangiectasia	✔
Bare Lymphocyte Syndrome	✔
Common Variable Immunodeficiency	✔
DiGeorge Syndrome	✔
Hemophagocytic Lymphohistiocytosis	✔
Leukocyte Adhesion Deficiency	✔
Lymphoproliferative Disorders	✔
Lymphoproliferative Disorder, X-linked (Susceptibility to Epstein-Barr virus)	✔
Wiskott-Aldrich Syndrome	✔
Myeloproliferative Disorders:	…	…
Acute Myelofibrosis	✔
Agnogenic Myeloid Metaplasia (Myelofibrosis)	✔
Polycythemia Vera	✔
Essential Thrombocythemia	✔
Phagocyte Disorders These are immune system cells that engulf and kill foreign organisms:	…	…
Chediak-Higashi Syndrome	✔
Chronic Granulomatous Disease	✔
Neutrophil Actin Deficiency	✔
Reticular Dysgenesis	✔
Bone Marrow Cancers:	…	…
Multiple Myeloma	✔	✔
Plasma Cell Leukemia	✔	✔
Waldenstrom’s Macroglobulinemia	✔	✔

Transplants for Inherited Disorders of the Immune System & Other Organs

Diagnosis	Allogeneic (Donor Cells)	Autologous (Own Cells)
Cartilage-Hair Hypoplasia	✔
Erythropoietic Porphyria	✔
Hermansky-Pudlak Syndrome	✔
Pearson’s Syndrome	✔
Shwachman-Diamond Syndrome	✔
Systemic Mastocytosis	✔

Transplants for Inherited Metabolic Disorders

Diagnosis	Allogeneic (Donor Cells)	Autologous (Own Cells)
Mucopolysaccharidosis (MPS) Storage Diseases:	…	…
Hurler Syndrome (MPS-IH)	✔
Scheie Syndrome (MPS-IS)	✔
Hunter Syndrome (MPS-II)	✔
Sanfilippo Syndrome (MPS-III)	✔
Morquio Syndrome (MPS-IV)	✔
Maroteaux-Lamy Syndrome (MPS-VI)	✔
Sly Syndrome (MPS-VII) (beta-glucuronidase deficiency)	✔
Mucolipidosis II (I-cell Disease)	✔
Leukodystrophy Disorders:	…	…
Adrenoleukodystrophy (ALD)	✔
Krabbe Disease(Globoid Cell Leukodystrophy)	✔
Metachromatic Leukodystrophy	✔
Pelizaeus-Merzbacher Disease	✔
Lysosomal Storage Diseases:	…	…
Niemann-Pick Disease	✔
Sandhoff Disease	✔
Wolman Disease	✔
Other Inherited Metabolic Disorders:	…	…
Lesch-Nyhan Syndrome	✔
Osteopetrosis	✔

Solid tumors not originating in the blood or immune system

Diagnosis	Allogeneic (Donor Cells)	Autologous (Own Cells)
Neuroblastoma		✔
Medulloblastoma		✔
Retinoblastoma		✔

Neurologic Disorder

Diagnosis	Cord Blood Allogeneic (Donor Cells)	Cord Blood Autologous (Own Cells)	Cord Tissue Allogeneic (Donor Cells)
Alzheimer’s disease	✔		✔
Autism	✔	✔	✔
Cerebral Palsy	✔	✔	✔
Encephalopathy		✔
Global Developmental Delay	✔	✔
Hearing Loss (acquired sensorineural)		✔
Intraventricular Hemorrhage	✔	✔
Parkinson’s disease	✔		✔
Spinal Cord Injury	✔		✔
Stroke	✔	✔	✔
Traumatic Brain Injury	✔	✔	✔

Auto-Immune Disorders

Diagnosis	Cord Blood Allogeneic (Donor Cells)	Cord Blood Autologous (Own Cells)	Cord Tissue Allogeneic (Donor Cells)
Alopecia Areata	✔
Amyotrophic Lateral Sclerosis (ALS)	✔		✔
Crohn’s Disease	✔
Eczema (Atopic Dermatitis)	✔
Graft-versus-Host Disease (GvHD)	✔		✔
Lupus	✔		✔
Multiple Sclerosis			✔
Psoriasis			✔
Rheumatoid Arthritis	✔		✔
Scleroderma
Systemic Sclerosis	✔
Ulcerative Colitis			✔

Cardiovascular

Diagnosis	Cord Blood Allogeneic (Donor Cells)	Cord Blood Autologous (Own Cells)	Cord Tissue Allogeneic (Donor Cells)
Acute Myocardial Infarction (Heart Attack)			✔
Cardiomyopathy			✔
Critical Limb Ischemia (CLI)	✔		✔
Heart Failure			✔
Peripheral Arterial Disease (PAD)	✔		✔
Surgery for Congenital Heart Defects		✔

Diabetic

Diagnosis	Cord Blood Allogeneic (Donor Cells)	Cord Blood Autologous (Own Cells)	Cord Tissue Allogeneic (Donor Cells)
Diabetes, Type 1 (this is Auto-Immune)	✔	✔
Diabetes, Type 2	✔	✔	✔
Diabetic Foot Ulcer			✔
Diabetic Peripheral Neuropathy			✔

Genetic and/or Metabolic Disorders

Diagnosis	Cord Blood Allogeneic (Donor Cells)	Cord Blood Autologous (Own Cells)	Cord Tissue Allogeneic (Donor Cells)
Aging Frailty	✔		✔
Duchenne Muscular Dystrophy			✔
Epidermolysis Bullosa	✔
Hereditary Ataxia			✔
Lysosomal Storage Diseases	✔
Metabolic Syndrome			✔
Severe Combined Immunodeficiency		✔
Spinal muscular atrophy			✔
Tay-Sachs Disease	✔

Orthopedic

Diagnosis	Cord Blood Allogeneic (Donor Cells)	Cord Blood Autologous (Own Cells)	Cord Tissue Allogeneic (Donor Cells)
Ankylosing Spondylitis			✔
Cartilage Injury	✔		✔
Cleft Palate Repair			✔
Non-Union Fractures			✔
Osteoarthritis	✔		✔
Osteochondral Lesion	✔
Spinal Fusion Surgery			✔

Other

Diagnosis	Cord Blood Allogeneic (Donor Cells)	Cord Blood Autologous (Own Cells)	Cord Tissue Allogeneic (Donor Cells)
Acute Respiratory Distress Syndrome (ARDS)			✔
BronchoPulmonary Dysplasia (BPD) (lung disorder due to premature birth)	✔		✔
Erectile Dysfunction			✔
Eye Diseases	✔		✔
Fistula			✔
HIV	✔
Kidney Failure			✔
Liver Cirrhosis	✔		✔
Liver Failure	✔		✔
Peyronie’s Disease			✔
Premature Ovarian Failure	✔		✔
Uterine Scars			✔
Wounds			✔