78 Illness covered that can be treated by umbilical cord blood stem cell

Leukaemias

Leukaemia is a cancer of the blood immune system, cells are called leukocytes or white cells

  • Acute Lymphoblastic Leukaemia (ALL)
  • Acute Myelogenous Leukaemia (AML)
  • Acute Biphenotypic Leukaemia
  • Acute Undifferentiated Leukaemia
  • Chronic Lymphocytic Leukaemia (CLL)
  • Chronic Myelogenous Leukaemia (CML)
  • Juvenile Chronic Myelogenous Leukaemia (JCML)
  • Juvenile Myelomonocytic Leukaemia (JMML)

Myelodysplastic Syndromes

Myelodysplastic Syndromes are also called pre-leukaemia

  • Refractory Anaemia
  • Refractory Anaemia with Ringed Sideroblasts (Sideroblastic anemia)
  • Refractory Anaemia with Excess Blasts
  • Refractory Anaemia with Excess Blasts in Transformation
  • Chronic Myelomonocytic Leukaemia (CMML)

Lymphoma

Lymphoma is a cancer of the leukocytes that circulate in the blood and lymph vessels

  • Hodgkin’s Lymphoma
  • Non-Hodgkin’s Lymphoma (Burkitt’s Lymphoma)

Transplants for Inherited Disorders

Transplants for Inherited Disorders of the Immune System & Other Organs

  • Cartilage-Hair Hypoplasia
  • Erythropoietic Porphyria
  • Hermansky-Pudlak Syndrome
  • Pearson’s Syndrome
  • Shwachman-Diamond Syndrome
  • Systemic Mastocytosis

Solid Tumours

Solid tumors not originating in the blood or immune system

  • Neuroblastoma
  • Medulloblastoma
  • Retinoblastoma

Transplants for Inherited Metabolic Disorders

Mucopolysaccharidosis (MPS) Storage Diseases
  • Hurler Syndrome (MPS-IH)
  • Scheie Syndrome (MPS-IS)
  • Hunter Syndrome (MPS-II)
  • Sanfilippo Syndrome (MPS-III)
  • Morquio Syndrome (MPS-IV)
  • Maroteaux-Lamy Syndrome (MPS-VI)
  • Sly Syndrome (MPS-VII) (beta-glucuronidase deficiency)
  • Mucolipidosis II (I-cell Disease)
Leukodystrophy Disorders
  • Adrenoleukodystrophy (ALD)
  • Krabbe Disease(Globoid Cell Leukodystrophy)
  • Metachromatic Leukodystrophy
  • Pelizaeus-Merzbacher Disease
Lysosomal Storage Diseases
  • Niemann-Pick Disease
  • Sandhoff Disease
  • Wolman Disease
Other Inherited Metabolic Disorders
  • Lesch-Nyhan Syndrome
  • Osteopetrosis

Other Disorders of Blood Cell Proliferation

Anaemias are deficiencies or malformations of red cells
  • Aplastic Anaemia
  • Fanconi Anaemia (The first cord blood transplant in 1988 was for FA, an inherited disorder)
  • Congenital Dyserythropoietic Anaemia
  • Paroxysmal Nocturnal Hemoglobinuria (PNH)
Inherited Red Cell Abnormalities. Red cells contain haemoglobin and carry oxygen to the body
  • Sickle Cell Disease
  • Beta Thalassemia Major (aka Cooley’s Anaemia)
  • Diamond-Blackfan Anaemia
  • Pure Red Cell Aplasia
Inherited Platelet Abnormalities. Platelets are blood cells needed for clotting
  • Amegakaryocytosis / Congenital Thrombocytopenia
  • Glanzmann Thrombasthenia
Inherited Immune System Disorders: Neutropenias
  • Infantile Genetic Agranulocytosis (Kostmann Syndrome)
  • Myelokathexis
Inherited Immune System Disorders: Severe Combined Immunodeficiency
  • SCID with Adenosine Deaminase Deficiency (ADA-SCID)
  • SCID which is X-linked
  • SCID with absence of T & B Cells
  • SCID with absence of T Cells, Normal B Cells
  • Omenn Syndrome
Inherited Immune System Disorders: Other
  • Ataxia-Telangiectasia
  • Bare Lymphocyte Syndrome
  • Common Variable Immunodeficiency
  • DiGeorge Syndrome
  • Haemophagocytic lymphohistiocytosis
  • Leukocyte Adhesion Deficiency
  • Lymphoproliferative Disorders
  • Lymphoproliferative Disorder, X-linked (Susceptibility to Epstein-Barr virus)
  • Wiskott-Aldrich Syndrome
Myeloproliferative Disorders
  • Acute Myelofibrosis
  • Agnogenic Myeloid Metaplasia (Myelofibrosis)
  • Polycythemia Vera
  • Essential Thrombocythemia
Phagocyte Disorders – These are immune system cells that engulf and kill foreign organisms
  • Chediak-Higashi Syndrome
  • Chronic Granulomatous Disease
  • Neutrophil Actin Deficiency
  • Reticular Dysgenesis
Bone Marrow Cancers
  • Multiple Myeloma
  • Plasma Cell Leukaemia
  • Waldenstrom’s Macroglobulinemia Agnogenic Myeloid Metaplasia (Myelofibrosis)